Only one thing was for sure after Grace Potter and the Nocturnals closed out their run of primarily sold out shows last Saturday night at Lupo’s Heartbreak Hotel in Providence, R.I. Grace Potter definitely has some of that “Medicine” she sings about. Potter is the long-legged, prodigal mistress of rock ‘n roll who, accompanied by four acid rockers, is impossible to forget.

Rolling Stone Magazine called them one of the best new bands of 2010, but the only thing that is new about them is their sound on their June 2010 release, “Grace Potter and The Nocturnals.” The Vermont-based group released their first full-length album in 2005. In the past year, they performed at Bonnaroo Music Festival and live on VH1, as well as all over the late night television scene.

When Grace Potter and The Nocturnals took the stage at Lupo’s, they impressed visually before they even got the chance to stun the crowd musically. Dressed to the nines, the men sported tight dress pants and an assortment of vests and blazers, making them cool enough to rock but snazzy enough to share the stage with their gorgeous female band members. Bassist Cat Popper grooved with effortless sex appeal in skin-tight black pants and a sleeveless black, sequined top while teetering on four inch heels. Front-woman and organist Potter shimmered in an ensemble that featured sparkles from her eye shadow all the way down to her strappy, sky-high dress heels.

Then Potter began to sing. At the sound of her voice, all awareness of time and space were lost as the audience fell mesmerized to its virtue. Potter’s pipes delivered a handful of notes that most did not even know existed. Her melodies stole the hearts of the masses in the way of a darling pop singer and locked them away when she unveiled her soulful sound on the bluesy tunes. With these multifaceted vocal capabilities, she demonstrated that she was comfortably at the highest rung of singers. Potter’s voice never faltered, instead leading the Nocturnals through an irrepressible set.

The Nocturnals, a foursome of individually skilled musicians, became one addictive amplification through a shared infatuation with psychedelic rock. Every member was a powerhouse of unrelenting rock ‘n’ roll. They appeared and sounded like they owned the stage and had for decades. Each member worked in constant connection with one another as if they were pieces of one musical mind. The audience bore witness to a seamless and rare dynamic that was only possible because of the entities who created it.

Early on in the set, the group plunged into the mysterious “Oasis” off of their 2010 self-titled release. Revealing great stamina they executed a perfectly steady and slow increase of speed and sound when they reached the bridge. For what felt like days the tension hung heavy among the high ceilings, begging to be released.

As the Nocturnals strummed and drummed harder and faster, Potter sang monosyllables like a siren. With this accompaniment she proved that her voice is a powerful instrument. When the song reached resolution the audience erupted. They were officially along for the dusty, dauntless Mustang convertible ride that was the GPN set that night.

Smoothing the cool bass formations was Popper, a supermodel-esque brunette who never stopped driving the soul of their jams. Popper shone brightly on “Oasis” and the mind-bending cover of Jefferson Airplane’s “White Rabbit,” the latter of which she introduced with an ominous, pulsating line. Though she only joined the group in 2009, it was evident that her addition greatly contributed to the band’s now refined vibe.

Alongside Popper were the intricate guitar stylings of Benny Yurco, also a 2009 addition to the Nocturnals. His fingers rapidly danced across his acoustic guitar, generating as much energy as when he picked up his electric to shred, a memorable feat. The New Jersey native elicited minutes of continuous cheers when he stood alone on stage to perform an extended acoustic intro to their cover of Heart’s “Crazy On You.” The solo was so complex, it crafted the auditory illusion that several guitarists were performing.

Yurco was also featured during a throwback blues cover tune where he, Potter and lead guitarist, Scotty Tournet, all strapped on acoustic guitars. The crowd savored every unified moment the trio played together. They basked as Potter bore her “old soul,” telling a sentimental story of Memphis, Tenn. in her best country voice.

Maxing out the decibel capacity at Lupo’s was the unstoppable Scotty Tournet on lead guitar. One of the original three band members, he jammed like his and his bandmates’ lives depended on it. During each bridge solo, he looked like he might run out of frets on the guitar as his fingers flew all the way up the neck and back again. His chemistry with Potter in particular was hard to miss.

Tournet and Potter vibed strongly off of each other when she donned her famous white Gibson Flying V for “Paris (Ooh La La).” The amplitude from this song threatened to rattle the antique chandeliers from the walls of Lupo’s. Potter and the Nocturnals got the entire crowd involved in singing the chorus, having just as much of a riot as the ticket holders did.

Driving the velocity home was the other original band member, drummer Matt Burr. Burr and Potter found each other at St. Lawrence University. On the set, Burr rocks a perpetual smile and a tireless playing style. With pin-straight, shoulder-length blond hair and classic rock-inspired technique, Burr looks and sounds like he stepped right out of the 70s.

Potter and the Nocturnals spewed sexuality from their amplifiers while maintaining an edgy wildness that stems from their Vermont roots. Their tunes were often reminiscent of gritty southern blues, but were executed in an alluring, psychedelic manner. This group, headed by the Jim Morrison-esque belting, undeniably alluring Potter, sets itself far apart from the everyday rock combo.

But the vital ingredient, and the reason why they’re now untouchable isn’t the “three cups bottled lightening” of which Potter sings. It is the golden haired, golden-hearted gem that shines from the inside out. It’s Potter.

Amy Larson can be reached at [email protected].